Synthèse de dérivés coumariniques d’intérêts biologiques et antioxydants

Abstract : As part of the work developed on coumarin and other flavonoids in our laboratory (aurones as potential NFK-B inhibitors, chromanic polycycles as CDC25 phosphatases inhibitors), the aim of this thesis was to pursue the research in this area by synthesizing new chalcones from acetylated coumarines derivatives by condensation with cynnamic aldehydes prepared by different methods. The prepared chalcones were studied for their antioxidant activity using spectrophotometry and for their inhibition of CDC25 phosphatases
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Theses
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http://docnum.univ-lorraine.fr/prive/DDOC_T_2015_0335_DRIDI.pdf
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Submitted on : Friday, March 30, 2018 - 9:56:53 AM
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Delel Dridi. Synthèse de dérivés coumariniques d’intérêts biologiques et antioxydants. Autre. Université de Lorraine, 2015. Français. ⟨NNT : 2015LORR0335⟩. ⟨tel-01754665⟩

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