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Développement d'une prothèse de resurfaçage de métatarsiens et étude du remodelage osseux induit

Abstract : This doctoral thesis, the result of a collaboration between LEMTA laboratory and Novastep company, explains the design of a metatarsal head resurfacing prosthesis of the lateral toes (2nd, 3rd and 4th toes). These toes can be affected by several pathologies, including arthritis and Freiberg’s disease, which are painful and can bec ripping in everyday life. Although many prosthetic solutions for the resurfacing of the metatarsal heads are available on the market, they are often developed for the first toe only. Novastep’s prosthesis was developed to afford a viable solution for the treatment of those pathologies in other toes as well. The development of this prosthesis requires several steps which are: • The definition of medical and mechanical requirements which must been taken into account ; • The design of the prosthesis ; • The development of the surgical technique, that is, the instrumentation for setting up the prosthesis ; • Mechanical and clinical testing to verify the performance of the prosthesis. This design cycle permits justification of the device’s performance necessary to obtain the market approval. In parallel with the resurfacing prosthesis, a study of metatarsal bone remodeling after implantation was realized. This study aimed to present and validate a protocol for the preparation of finite element models of bone remodeling from patient specific computed-tomography data. It also permitted analysis of the impact of the Novastep’s prosthesis on the metatarsal and comparison of those resuts with results obtained with a competitor’s equivalent prosthesis (LMHI of Wright Medical). To our knowledge, this study was the first on the bone remodeling of a prosthetic metatarsal. In the long term, this work could lead to the creation of a decision-making tool for designers for the technological choices of prosthesis design
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Submitted on : Tuesday, November 20, 2018 - 10:07:06 AM
Last modification on : Wednesday, November 3, 2021 - 5:38:50 AM


  • HAL Id : tel-01927757, version 1


Yohann Couqueberg. Développement d'une prothèse de resurfaçage de métatarsiens et étude du remodelage osseux induit. Ingénierie biomédicale. Université de Lorraine, 2018. Français. ⟨NNT : 2018LORR0117⟩. ⟨tel-01927757⟩



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