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Master thesis

Hyperfixations colorectales et anales en morpho-teps au 18F-FDG : confrontation aux données endoscopiques et anatomopathologiques

Abstract : Purpose : our aim was to identify the critena of visual and quantitative analysis of colorectal and anal uptake likely to predict their benign or malignant origin. Materials and methods : the reported database of 13400 patients who underwent whole-body [exponent 18]FDG PET/CT scans from January 2003 to October 2007 was reviewed. Three hundred and eighty two patients who presented at least one colorectal or anal site of FDG uptake were included. The PET/CT examinations were interpreted with regard to the location and visual characteristics of FDG uptake as well as semiquantitative SUV parameter and volume of FDG uptake. The irnaging resuts were compared with endoscopic and histopathologic data which were available for 113 patients and 131 lesions.Results : visual features discriminating significantly patients with neoplasm (precancerous lesion or cancer) from patients without were the uptake type (homogeneous or heterogeneous) and the presence or not of wall thickening or intraluminal mass. A significant difference of SUVmax and volume ofFDG uptake was found hetween the cases with neoplasm and the cases without.Conclusion : colorectal uptake characterization in PET/CT permits to support or to discard its neoplastic origin, to decrease the false positive rate and therefore to adequatly identify the patients to be investigated with colonoscopy.
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Master thesis
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https://hal.univ-lorraine.fr/hal-01732346
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Submitted on : Wednesday, March 14, 2018 - 2:56:13 PM
Last modification on : Friday, October 23, 2020 - 5:01:30 PM
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  • HAL Id : hal-01732346, version 1

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Thomas Poisson. Hyperfixations colorectales et anales en morpho-teps au 18F-FDG : confrontation aux données endoscopiques et anatomopathologiques. Sciences du Vivant [q-bio]. 2008. ⟨hal-01732346⟩

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