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Master thesis

Propriétés de surface et d’adhésion de Parabacteroides distasonis

Abstract : Parabacteroides distasonis is a bacterium of the gut microbiota whose beneficial roles for the host, at metabolic and immune level, suggest its importance in the core microbiome. Previous studies show a significant loss of this taxon as a result of socio-environmental or hypergravity stress applied to its host. The purpose of this study is to determine some surface and adhesion properties of this species, particularly on abiotic support and CaCo-2 intestinal cell line. Results show a moderate adhesion power on both types of support, with one strain strongly adhering on an inert support and two strains strongly adhering on gut cells. This moderate adhesion seems to be due to a moderate permeability and a low electronegativity due to the presence of a capsule and lipopolysaccharides on the surface of these bacteria. These results provide a starting point for studying the precise mechanisms of these phenomena, with the aim of preventing the loss of this species within the intestinal microbiota.
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Master thesis
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Submitted on : Monday, April 20, 2020 - 3:45:18 PM
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  • HAL Id : hal-02548274, version 1


Thibault Carlier. Propriétés de surface et d’adhésion de Parabacteroides distasonis. Microbiologie et Parasitologie. 2019. ⟨hal-02548274⟩



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