Physicochemical degradation of phycocyanin and means to improve its stability: A short review - Archive ouverte HAL Access content directly
Journal Articles Journal of Pharmaceutical Analysis Year : 2021

Physicochemical degradation of phycocyanin and means to improve its stability: A short review

(1) , (1) , (2, 3) , (4) , (1)
1
2
3
4

Abstract

The cyanobacterium Arthrospira platensis, spirulina, is a source of pigments such as phycobiliprotein, phycocyanin. Phycocyanin is used in the food, cosmetic, and pharmaceutical industries because of its antioxidant, anti-inflammatory, and anticancer properties. The different steps involved in extraction and purification of this protein can alter the final properties. In this review, the stability of phycocyanin (pH, temperature, and light) is discussed, considering the physicochemical parameters of kinetic modeling. The optimal working pH range for phycocyanin is between 5.5 and 6.0 and it remains stable up to 45 °C; however, exposure to relatively high temperatures or acidic pH decreases its half-life and increases the degradation kinetic constant. Phycobiliproteins are sensitive to light and preservatives such as mono- and di-saccharides, citric acid, or sodium chloride appear to be effective stabilizing agents. Encapsulation within nano- or micro-structured materials such as nanofibers, microparticles, or nanoparticles, can also preserve or enhance its stability.
Fichier principal
Vignette du fichier
Marchioni_1-s2.0-S2095177921001489-main.pdf (1.71 Mo) Télécharger le fichier

Dates and versions

hal-03511791 , version 1 (10-02-2022)

Identifiers

Cite

Aida Adjali, Igor Clarot, Zilin Chen, Eric Marchioni, Ariane Boudier. Physicochemical degradation of phycocyanin and means to improve its stability: A short review. Journal of Pharmaceutical Analysis, 2021, ⟨10.1016/j.jpha.2021.12.005⟩. ⟨hal-03511791⟩
102 View
21 Download

Altmetric

Share

Gmail Facebook Twitter LinkedIn More