Interactions between Bacteria and Aspergillus fumigatus in Airways: From the Mycobiome to Molecular Interactions
Résumé
Interactions between different kingdoms of microorganisms in humans are common but not well described. A recent analysis of the mycobiome has described the presence of different fungi and their positive and/or negative interactions with bacteria and other fungi. In chronic respiratory diseases, these different microorganisms form mixed biofilms to live inside. The interactions between Gram-negative bacteria and filamentous fungi in these biofilms have attracted more attention recently. In this review, we analyse the microbiota of the respiratory tract of healthy individuals and patients with chronic respiratory disease. Additionally, we describe the regulatory mechanisms that rule the mixed biofilms of Aspergillus fumigatus and Gram-negative bacteria and the effects of this biofilm on clinical presentations.
Mots clés
Debourgogne
A. Monpierre
L. Sy
K.A. Valsecchi
I. Decousser
J.-W. Botterel
F. Interactions between Bacteria and Aspergillus fumigatus Pseudomonas aeruginosa Stenotrophomonas maltophilia polymicrobial biofilms mixed biofilm
A.
Monpierre
L.
Sy
K.A.
Valsecchi
I.
Decousser
J.-W.
Botterel
F. Interactions between Bacteria and Aspergillus fumigatus
Pseudomonas aeruginosa
Stenotrophomonas maltophilia
polymicrobial biofilms
mixed biofilm
Debourgogne
Domaines
Mycologie
Origine : Fichiers éditeurs autorisés sur une archive ouverte