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Etude biomécanique de substituts osseux en titane poreux destinés à la chirurgie maxillo-faciale

Abstract : This thesis deals with the development of patient specific porous titanium implants for maxillo-facial surgery. Once the mechanical properties of Selective Laser Melted commercially pure grade 2 titanium were characterized, finite elements simulations were carried out to create an elementary pattern with mechanical properties close to those of human bone.Weakening the initial properties of titanium enables to avoid the bone resorption phenomenon that frequently leads to prosthesis loosening. The ability of bone to grow into the porosities of the designed structure ensures optimal osseointegration of the implants.A new surface treatment composed of an immersion in sodium hydroxyde followed by an anodic oxydation was developed to improve the substitute integration to bone. This treatment enables to create a new oxyde layer on titanium with which bone will quickly create strong chemical links.We designed a patient specific numerical model in order to check the impact of cranial substitutes made of various materials on the modification of temperature fields in the head. Porous titanium implant and bone showed very similar thermal responses. Therefore, a porous titanium implant provides excellent thermal protection of brain. This model was set against a simplified one where the head was considered as a sphere. Since the results of these models were very similar, we concluded that the simplified modelling is appropriate to quickly predict temperature fields in the head with implant.So far, several porous bone substitutes based on the elementary pattern developed in this thesis were successfully implanted in humans
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Submitted on : Thursday, March 29, 2018 - 12:00:05 PM
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Alexandre Barbas. Etude biomécanique de substituts osseux en titane poreux destinés à la chirurgie maxillo-faciale. Autre. Université Paul Verlaine - Metz, 2011. Français. ⟨NNT : 2011METZ030S⟩. ⟨tel-01749065⟩



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