Skip to Main content Skip to Navigation
New interface

Mesure de bioimpédance électrique par capteurs interdigités

Abstract : The characterization by impedance spectroscopy of biological micro samples is one of the objectives of this thesis. The well known polarization phenomena at low frequency is a constraint that increases the measurement error. The main objective of this thesis is to optimize the geometric structure of an interdigitated electrode sensor in order to obtain confident experimental results in an extended useful frequency band without a significant influence of the polarization effect. The first chapter synthesizes fundamental data on the electrical behavior of biological tissues and their electrical properties. A state of the art techniques of the fundamental impedance measurement based on micrometric electrodes is also presented. The second chapter developps a theoretical approach for optimization of the biosensor. This optimization is used to expand the usable measurement. Indeed, it leads to determine the optimum distance between electrodes versus electrode width. A 3D modeling of the electrode system loaded by a biological medium was simulated using ConventorWare and the results are discussed. In the third chapter, the devices developed in this work are described. Design and manufacture of the biosensor components are described. In the last chapter, measurements on microvolumes of fluids (standard solutions, human blood) using five micros sensors with interdigitated electrodes are presented and discussed. Finally we compare these results to published values in the literature and the optimization theory is experimentally validated
Complete list of metadata

Cited literature [95 references]  Display  Hide  Download
Contributor : Thèses UL Connect in order to contact the contributor
Submitted on : Thursday, March 29, 2018 - 12:22:22 PM
Last modification on : Friday, October 23, 2020 - 5:01:27 PM
Long-term archiving on: : Monday, September 17, 2018 - 12:36:53 PM


Files produced by the author(s)


  • HAL Id : tel-01749652, version 1



Mouhamad Ibrahim. Mesure de bioimpédance électrique par capteurs interdigités. Médecine humaine et pathologie. Université de Lorraine, 2012. Français. ⟨NNT : 2012LORR0307⟩. ⟨tel-01749652⟩



Record views


Files downloads